Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression

Tumor-associated macrophages (TAMs) are a highly plastic stromal cell type that support cancer progression. Using single-cell RNA sequencing of TAMs from a spontaneous murine model of mammary adenocarcinoma (MMTV-PyMT), we characterize a subset of these cells expressing lymphatic vessel endothelial...

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Detalles Bibliográficos
Autores principales: Opzoomer, James W., Anstee, Joanne E., Dean, Isaac, Hill, Emily J., Bouybayoune, Ihssane, Caron, Jonathan, Muliaditan, Tamara, Gordon, Peter, Sosnowska, Dominika, Nuamah, Rosamond, Pinder, Sarah E., Ng, Tony, Dazzi, Francesco, Kordasti, Shahram, Withers, David R., Lawrence, Toby, Arnold, James N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565907/
https://www.ncbi.nlm.nih.gov/pubmed/34730997
http://dx.doi.org/10.1126/sciadv.abg9518

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