Cargando…

Broussochalcone A Induces Apoptosis in Human Renal Cancer Cells via ROS Level Elevation and Activation of FOXO3 Signaling Pathway

Broussochalcone A (BCA) is a chalcone compound extracted from the cortex of Broussonetiapapyrifera (L.) Ventenat that exerts various effects, such as potent antioxidant, antiplatelet, and anticancer effects. However, the effects of BCA against cancers have been seldom studied. This study is aimed at...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Han Ki, Cha, Hyo Sun, Nam, Myeong Jin, Park, Kyungmoon, Yang, Yung-Hun, Lee, Jongsung, Park, See-Hyoung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566040/ https://www.ncbi.nlm.nih.gov/pubmed/34745413 http://dx.doi.org/10.1155/2021/2800706

Ejemplares similares

Acetylshikonin, A Novel CYP2J2 Inhibitor, Induces Apoptosis in RCC Cells via FOXO3 Activation and ROS Elevation
por: Lim, Heui Min, et al.
Publicado: (2022)

Acetylshikonin Induces Apoptosis in Human Colorectal Cancer HCT-15 and LoVo Cells via Nuclear Translocation of FOXO3 and ROS Level Elevation
por: Lim, Heui Min, et al.
Publicado: (2021)

6,8-Diprenylorobol Induces Apoptosis in Human Hepatocellular Carcinoma Cells via Activation of FOXO3 and Inhibition of CYP2J2
por: Lee, Chang Min, et al.
Publicado: (2020)

Mitoxantrone induces apoptosis in osteosarcoma cells through regulation of the Akt/FOXO3 pathway
por: Park, See-Hyoung, et al.
Publicado: (2018)

Indole-3-Carbinol Induces Apoptosis in Human Osteosarcoma MG-63 and U2OS Cells
por: Lee, Chang Min, et al.
Publicado: (2018)

Broussochalcone A Is a Novel Inhibitor of the Orphan Nuclear Receptor NR4A1 and Induces Apoptosis in Pancreatic Cancer Cells
por: Lee, Hyo-Seon, et al.
Publicado: (2021)

IL13Rα2 Is Involved in the Progress of Renal Cell Carcinoma through the JAK2/FOXO3 Pathway
por: Kang, Mi-Ae, et al.
Publicado: (2021)

Tomentosin Displays Anti-Carcinogenic Effect in Human Osteosarcoma MG-63 Cells via the Induction of Intracellular Reactive Oxygen Species
por: Lee, Chang Min, et al.
Publicado: (2019)

Knockout of Hepatocyte Growth Factor by CRISPR/Cas9 System Induces Apoptosis in Hepatocellular Carcinoma Cells
por: Lee, Han Ki, et al.
Publicado: (2021)

Interleukin4Rα (IL4Rα) and IL13Rα1 Are Associated with the Progress of Renal Cell Carcinoma through Janus Kinase 2 (JAK2)/Forkhead Box O3 (FOXO3) Pathways
por: Kang, Mi-Ae, et al.
Publicado: (2019)

Isolation of Microbulbifer sp. SOL66 with High Polyhydroxyalkanoate-Degrading Activity from the Marine Environment
por: Park, Sol Lee, et al.
Publicado: (2021)

IL4Rα and IL13Rα1 Are Involved in the Development of Human Gallbladder Cancer
por: Ahn, Sung Woo, et al.
Publicado: (2022)

Antiwrinkle and antimelanogenesis activity of the ethanol extracts of Lespedeza cuneata G. Don for development of the cosmeceutical ingredients
por: Lee, Jongsung, et al.
Publicado: (2018)

Poly(3-hydroxybutyrate) Degradation by Bacillus infantis sp. Isolated from Soil and Identification of phaZ and bdhA Expressing PHB Depolymerase
por: Jeon, Yubin, et al.
Publicado: (2023)

Association between Olfactory Receptors and Skin Physiology
por: Seo, Jinyoung, et al.
Publicado: (2022)

Acceleration of Polybutylene Succinate Biodegradation by Terribacillus sp. JY49 Isolated from a Marine Environment
por: Kim, Su Hyun, et al.
Publicado: (2022)

Novel Polyhydroxybutyrate-Degrading Activity of the Microbulbifer Genus as Confirmed by Microbulbifer sp. SOL03 from the Marine Environment
por: Park, Sol Lee, et al.
Publicado: (2022)

Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo
por: Park, See-Hyoung, et al.
Publicado: (2016)

Mitochondrial ROS activates ERK/autophagy pathway as a protected mechanism against deoxypodophyllotoxin-induced apoptosis
por: Kim, Sang-Hun, et al.
Publicado: (2017)

Recent Advances in the Chemobiological Upcycling of Polyethylene Terephthalate (PET) into Value-Added Chemicals
por: Mudondo, Joyce, et al.
Publicado: (2023)

Juglanthraquinone C Induces Intracellular ROS Increase and Apoptosis by Activating the Akt/Foxo Signal Pathway in HCC Cells
por: Hou, Ya-Qin, et al.
Publicado: (2016)

The Role of Adiponectin in the Skin
por: Oh, Jieun, et al.
Publicado: (2022)

Stemness and differentiation potential-recovery effects of sinapic acid against ultraviolet-A-induced damage through the regulation of p38 MAPK and NF-κB
por: Hwang, Young Sun, et al.
Publicado: (2017)

αMSH prevents ROS-induced apoptosis by inhibiting Foxo1/mTORC2 in mice adipose tissue
por: Cao, Weina, et al.
Publicado: (2017)

Melatonin alleviates pyroptosis by regulating the SIRT3/FOXO3α/ROS axis and interacting with apoptosis in Atherosclerosis progression
por: Cong, Lin, et al.
Publicado: (2023)

Suppression of FoxO6 by lipopolysaccharide in aged rat liver
por: Kim, Dae Hyun, et al.
Publicado: (2015)

Metformin Attenuates ROS via FOXO3 Activation in Immune Cells
por: Hartwig, Jelka, et al.
Publicado: (2021)

High cholesterol induces apoptosis and autophagy through the ROS-activated AKT/FOXO1 pathway in tendon-derived stem cells
por: Li, Kaiqun, et al.
Publicado: (2020)

Melatonin-Mediated Suppression of mtROS-JNK-FOXO1 Pathway Alleviates Hypoxia-Induced Apoptosis in Porcine Granulosa Cells
por: Zhang, Xuan, et al.
Publicado: (2023)

Glycolaldehyde, an Advanced Glycation End Products Precursor, Induces Apoptosis via ROS-Mediated Mitochondrial Dysfunction in Renal Mesangial Cells
por: Gu, Min Ji, et al.
Publicado: (2022)

The relationship of skin disorders, COVID-19, and the therapeutic potential of ginseng: a review
por: Yang, Seoyoun, et al.
Publicado: (2023)

REP1 inhibits FOXO3-mediated apoptosis to promote cancer cell survival
por: Song, Kwon-Ho, et al.
Publicado: (2017)

Quercetin induces apoptosis and cell cycle arrest in triple-negative breast cancer cells through modulation of Foxo3a activity
por: Nguyen, Lich Thi, et al.
Publicado: (2017)

FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage
por: Chung, Young Min, et al.
Publicado: (2012)

Crebanine induces ROS-dependent apoptosis in human hepatocellular carcinoma cells via the AKT/FoxO3a signaling pathway
por: Tan, Jiajie, et al.
Publicado: (2023)

Licochalcone B Induces ROS-Dependent Apoptosis in Oxaliplatin-Resistant Colorectal Cancer Cells via p38/JNK MAPK Signaling
por: Kwak, Ah-Won, et al.
Publicado: (2023)

Cinnamaldehyde and Hyperthermia Co-Treatment Synergistically Induces ROS-Mediated Apoptosis in ACHN Renal Cell Carcinoma Cells
por: Ahn, Chae Ryeong, et al.
Publicado: (2020)

Anti-Proliferative and Pro-Apoptotic Effects of Licochalcone A through ROS-Mediated Cell Cycle Arrest and Apoptosis in Human Bladder Cancer Cells
por: Hong, Su Hyun, et al.
Publicado: (2019)

PD‐L1 expression in ROS1‐rearranged non‐small cell lung cancer: A study using simultaneous genotypic screening of EGFR, ALK, and ROS1
por: Lee, Jongmin, et al.
Publicado: (2018)

FoxO6 inhibits melanogenesis partly by elevating intracellular antioxidant capacity
por: Moon, Kyoung Mi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3h7t701aifqd2u7k6v2s1q8q16