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Targeting HSPA1A in ARID2-deficient lung adenocarcinoma

Somatic mutations of the chromatin remodeling gene ARID2 are observed in ∼7% of human lung adenocarcinomas (LUADs). However, the role of ARID2 in the pathogenesis of LUADs remains largely unknown. Here we find that ARID2 expression is decreased during the malignant progression of both human and mice...

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Detalles Bibliográficos
Autores principales: Wang, Xue, Wang, Yuetong, Fang, Zhaoyuan, Wang, Hua, Zhang, Jian, Zhang, Longfu, Huang, Hsinyi, Jiang, Zhonglin, Jin, Yujuan, Han, Xiangkun, Hou, Shenda, Zhou, Bin, Meng, Feilong, Chen, Luonan, Wong, Kwok-Kin, Liu, Jinfeng, Zhang, Zhiqi, Zhang, Xin, Chen, Haiquan, Sun, Yihua, Hu, Liang, Ji, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566174/
https://www.ncbi.nlm.nih.gov/pubmed/34858604
http://dx.doi.org/10.1093/nsr/nwab014