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Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram
Charting an organs’ biological atlas requires us to spatially resolve the entire single-cell transcriptome, and to relate such cellular features to the anatomical scale. Single-cell and single-nucleus RNA-seq (sc/snRNA-seq) can profile cells comprehensively, but lose spatial information. Spatial tra...
Autores principales: | Biancalani, Tommaso, Scalia, Gabriele, Buffoni, Lorenzo, Avasthi, Raghav, Lu, Ziqing, Sanger, Aman, Tokcan, Neriman, Vanderburg, Charles R., Segerstolpe, Åsa, Zhang, Meng, Avraham-Davidi, Inbal, Vickovic, Sanja, Nitzan, Mor, Ma, Sai, Subramanian, Ayshwarya, Lipinski, Michal, Buenrostro, Jason, Brown, Nik Bear, Fanelli, Duccio, Zhuang, Xiaowei, Macosko, Evan Z., Regev, Aviv |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566243/ https://www.ncbi.nlm.nih.gov/pubmed/34711971 http://dx.doi.org/10.1038/s41592-021-01264-7 |
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