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A genetic approach reveals different modes of action of prefoldins
The prefoldin complex (PFDc) was identified in humans as a co-chaperone of the cytosolic chaperonin T-COMPLEX PROTEIN RING COMPLEX (TRiC)/CHAPERONIN CONTAINING TCP-1 (CCT). PFDc is conserved in eukaryotes and is composed of subunits PFD1–6, and PFDc-TRiC/CCT folds actin and tubulins. PFDs also parti...
Autores principales: | Blanco-Touriñán, Noel, Esteve-Bruna, David, Serrano-Mislata, Antonio, Esquinas-Ariza, Rosa María, Resentini, Francesca, Forment, Javier, Carrasco-López, Cristian, Novella-Rausell, Claudio, Palacios-Abella, Alberto, Carrasco, Pedro, Salinas, Julio, Blázquez, Miguel Á, Alabadí, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566299/ https://www.ncbi.nlm.nih.gov/pubmed/34618031 http://dx.doi.org/10.1093/plphys/kiab348 |
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