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Pathology and Immunity After SARS-CoV-2 Infection in Male Ferrets Is Affected by Age and Inoculation Route
Improving COVID-19 intervention strategies partly relies on animal models to study SARS-CoV-2 disease and immunity. In our pursuit to establish a model for severe COVID-19, we inoculated young and adult male ferrets intranasally or intratracheally with SARS-CoV-2. Intranasal inoculation established...
Autores principales: | van de Ven, Koen, van Dijken, Harry, Wijsman, Lisa, Gomersbach, Angéla, Schouten, Tanja, Kool, Jolanda, Lenz, Stefanie, Roholl, Paul, Meijer, Adam, van Kasteren, Puck B., de Jonge, Jørgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566349/ https://www.ncbi.nlm.nih.gov/pubmed/34745122 http://dx.doi.org/10.3389/fimmu.2021.750229 |
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