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The Click-On gamma probe, a second-generation tethered robotic gamma probe that improves dexterity and surgical decision-making

PURPOSE: Decision-making and dexterity, features that become increasingly relevant in (robot-assisted) minimally invasive surgery, are considered key components in improving the surgical accuracy. Recently, DROP-IN gamma probes were introduced to facilitate radioguided robotic surgery. We now studie...

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Autores principales: Azargoshasb, Samaneh, van Alphen, Simon, Slof, Leon J., Rosiello, Giuseppe, Puliatti, Stefano, van Leeuwen, Sven I., Houwing, Krijn M., Boonekamp, Michael, Verhart, Jeroen, Dell’Oglio, Paolo, van der Hage, Jos, van Oosterom, Matthias N., van Leeuwen, Fijs W. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566398/
https://www.ncbi.nlm.nih.gov/pubmed/34031721
http://dx.doi.org/10.1007/s00259-021-05387-z
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author Azargoshasb, Samaneh
van Alphen, Simon
Slof, Leon J.
Rosiello, Giuseppe
Puliatti, Stefano
van Leeuwen, Sven I.
Houwing, Krijn M.
Boonekamp, Michael
Verhart, Jeroen
Dell’Oglio, Paolo
van der Hage, Jos
van Oosterom, Matthias N.
van Leeuwen, Fijs W. B.
author_facet Azargoshasb, Samaneh
van Alphen, Simon
Slof, Leon J.
Rosiello, Giuseppe
Puliatti, Stefano
van Leeuwen, Sven I.
Houwing, Krijn M.
Boonekamp, Michael
Verhart, Jeroen
Dell’Oglio, Paolo
van der Hage, Jos
van Oosterom, Matthias N.
van Leeuwen, Fijs W. B.
author_sort Azargoshasb, Samaneh
collection PubMed
description PURPOSE: Decision-making and dexterity, features that become increasingly relevant in (robot-assisted) minimally invasive surgery, are considered key components in improving the surgical accuracy. Recently, DROP-IN gamma probes were introduced to facilitate radioguided robotic surgery. We now studied if robotic DROP-IN radioguidance can be further improved using tethered Click-On designs that integrate gamma detection onto the robotic instruments themselves. METHODS: Using computer-assisted drawing software, 3D printing and precision machining, we created a Click-On probe containing two press-fit connections and an additional grasping moiety for a ProGrasp instrument combined with fiducials that could be video tracked using the Firefly laparoscope. Using a dexterity phantom, the duration of the specific tasks and the path traveled could be compared between use of the Click-On or DROP-IN probe. To study the impact on surgical decision-making, we performed a blinded study, in porcine models, wherein surgeons had to identify a hidden (57)Co-source using either palpation or Click-On radioguidance. RESULTS: When assembled onto a ProGrasp instrument, while preserving grasping function and rotational freedom, the fully functional prototype could be inserted through a 12-mm trocar. In dexterity assessments, the Click-On provided a 40% reduction in movements compared to the DROP-IN, which converted into a reduction in time, path length, and increase in straightness index. Radioguidance also improved decision-making; task-completion rate increased by 60%, procedural time was reduced, and movements became more focused. CONCLUSION: The Click-On gamma probe provides a step toward full integration of radioguidance in minimal invasive surgery. The value of this concept was underlined by its impact on surgical dexterity and decision-making.
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spelling pubmed-85663982021-11-15 The Click-On gamma probe, a second-generation tethered robotic gamma probe that improves dexterity and surgical decision-making Azargoshasb, Samaneh van Alphen, Simon Slof, Leon J. Rosiello, Giuseppe Puliatti, Stefano van Leeuwen, Sven I. Houwing, Krijn M. Boonekamp, Michael Verhart, Jeroen Dell’Oglio, Paolo van der Hage, Jos van Oosterom, Matthias N. van Leeuwen, Fijs W. B. Eur J Nucl Med Mol Imaging Original Article PURPOSE: Decision-making and dexterity, features that become increasingly relevant in (robot-assisted) minimally invasive surgery, are considered key components in improving the surgical accuracy. Recently, DROP-IN gamma probes were introduced to facilitate radioguided robotic surgery. We now studied if robotic DROP-IN radioguidance can be further improved using tethered Click-On designs that integrate gamma detection onto the robotic instruments themselves. METHODS: Using computer-assisted drawing software, 3D printing and precision machining, we created a Click-On probe containing two press-fit connections and an additional grasping moiety for a ProGrasp instrument combined with fiducials that could be video tracked using the Firefly laparoscope. Using a dexterity phantom, the duration of the specific tasks and the path traveled could be compared between use of the Click-On or DROP-IN probe. To study the impact on surgical decision-making, we performed a blinded study, in porcine models, wherein surgeons had to identify a hidden (57)Co-source using either palpation or Click-On radioguidance. RESULTS: When assembled onto a ProGrasp instrument, while preserving grasping function and rotational freedom, the fully functional prototype could be inserted through a 12-mm trocar. In dexterity assessments, the Click-On provided a 40% reduction in movements compared to the DROP-IN, which converted into a reduction in time, path length, and increase in straightness index. Radioguidance also improved decision-making; task-completion rate increased by 60%, procedural time was reduced, and movements became more focused. CONCLUSION: The Click-On gamma probe provides a step toward full integration of radioguidance in minimal invasive surgery. The value of this concept was underlined by its impact on surgical dexterity and decision-making. Springer Berlin Heidelberg 2021-05-25 2021 /pmc/articles/PMC8566398/ /pubmed/34031721 http://dx.doi.org/10.1007/s00259-021-05387-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Azargoshasb, Samaneh
van Alphen, Simon
Slof, Leon J.
Rosiello, Giuseppe
Puliatti, Stefano
van Leeuwen, Sven I.
Houwing, Krijn M.
Boonekamp, Michael
Verhart, Jeroen
Dell’Oglio, Paolo
van der Hage, Jos
van Oosterom, Matthias N.
van Leeuwen, Fijs W. B.
The Click-On gamma probe, a second-generation tethered robotic gamma probe that improves dexterity and surgical decision-making
title The Click-On gamma probe, a second-generation tethered robotic gamma probe that improves dexterity and surgical decision-making
title_full The Click-On gamma probe, a second-generation tethered robotic gamma probe that improves dexterity and surgical decision-making
title_fullStr The Click-On gamma probe, a second-generation tethered robotic gamma probe that improves dexterity and surgical decision-making
title_full_unstemmed The Click-On gamma probe, a second-generation tethered robotic gamma probe that improves dexterity and surgical decision-making
title_short The Click-On gamma probe, a second-generation tethered robotic gamma probe that improves dexterity and surgical decision-making
title_sort click-on gamma probe, a second-generation tethered robotic gamma probe that improves dexterity and surgical decision-making
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566398/
https://www.ncbi.nlm.nih.gov/pubmed/34031721
http://dx.doi.org/10.1007/s00259-021-05387-z
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