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The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells

Epithelial-to-mesenchymal transition (EMT) is a transcriptionally governed process by which cancer cells establish a front-rear polarity axis that facilitates motility and invasion. Dynamic assembly of focal adhesions and other actin-based cytoskeletal structures on the leading edge of motile cells...

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Detalles Bibliográficos
Autores principales: Banerjee, Priyam, Xiao, Guan-Yu, Tan, Xiaochao, Zheng, Veronica J., Shi, Lei, Rabassedas, Maria Neus Bota, Guo, Hou-fu, Liu, Xin, Yu, Jiang, Diao, Lixia, Wang, Jing, Russell, William K., Roszik, Jason, Creighton, Chad J., Kurie, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566461/
https://www.ncbi.nlm.nih.gov/pubmed/34732702
http://dx.doi.org/10.1038/s41467-021-26677-y

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