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Single-cell RNA transcriptome reveals the intra-tumoral heterogeneity and regulators underlying tumor progression in metastatic pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is the most frequent and aggressive pancreatic tumor characterized by high metastatic risk and special tumor microenvironment. To comprehensively delineate the complex intra-tumoral heterogeneity and the underlying mechanism during metastatic lesions malignant...

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Detalles Bibliográficos
Autores principales: Xu, Qianhui, Chen, Shaohuai, Hu, Yuanbo, Huang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566471/
https://www.ncbi.nlm.nih.gov/pubmed/34732701
http://dx.doi.org/10.1038/s41420-021-00663-1