Selection for constrained peptides that bind to a single target protein

Peptide secondary metabolites are common in nature and have diverse pharmacologically-relevant functions, from antibiotics to cross-kingdom signaling. Here, we present a method to design large libraries of modified peptides in Escherichia coli and screen them in vivo to identify those that bind to a...

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Detalles Bibliográficos
Autores principales: King, Andrew M., Anderson, Daniel A., Glassey, Emerson, Segall-Shapiro, Thomas H., Zhang, Zhengan, Niquille, David L., Embree, Amanda C., Pratt, Katelin, Williams, Thomas L., Gordon, D. Benjamin, Voigt, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566587/
https://www.ncbi.nlm.nih.gov/pubmed/34732700
http://dx.doi.org/10.1038/s41467-021-26350-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566587/
https://www.ncbi.nlm.nih.gov/pubmed/34732700
http://dx.doi.org/10.1038/s41467-021-26350-4

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