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Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery

Purpose: To investigate the safety and efficacy of endovascular embolization of cerebral aneurysms at the P1–P3 segments of the posterior cerebral artery (PCA). Materials and Methods: Seventy-seven patients with 77 PCA aneurysms who were treated with endovascular embolization were enrolled, includin...

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Autores principales: Li, Xin-Yu, Li, Cong-Hui, Wang, Ji-Wei, Liu, Jian-Feng, Li, Hui, Gao, Bu-Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566677/
https://www.ncbi.nlm.nih.gov/pubmed/34744960
http://dx.doi.org/10.3389/fneur.2021.700516
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author Li, Xin-Yu
Li, Cong-Hui
Wang, Ji-Wei
Liu, Jian-Feng
Li, Hui
Gao, Bu-Lang
author_facet Li, Xin-Yu
Li, Cong-Hui
Wang, Ji-Wei
Liu, Jian-Feng
Li, Hui
Gao, Bu-Lang
author_sort Li, Xin-Yu
collection PubMed
description Purpose: To investigate the safety and efficacy of endovascular embolization of cerebral aneurysms at the P1–P3 segments of the posterior cerebral artery (PCA). Materials and Methods: Seventy-seven patients with 77 PCA aneurysms who were treated with endovascular embolization were enrolled, including 35 (45.5%) patients with ruptured aneurysms and 42 (54.5%) with unruptured ones. The pretreatment clinical data and aneurysm occlusion status after treatment and at follow-up were analyzed. Results: All patients were successfully treated endovascularly, including coiling alone in 10 (13.0%) patients, stent-assisted coiling in 18 (23.4%), parent artery occlusion in 25 (32.5%), and pipeline embolization device (PED) in 24 (31.2%). Complete occlusion was achieved in 48 (62.3%) aneurysms, residual neck in 4 (5.2%), and residual aneurysm in the other 25 (32.5%) at the end of embolization. Periprocedural complications occurred in eight patients, including acute thrombosis in seven (9.1%) and intraprocedural subarachnoid hemorrhage in one (1.3%), with the total complication rate of 10.4%. Follow-up was performed in 60 patients (77.9%) for 42 ± 11 months; the mRS score was 0–2 in 55 (91.7%) patients, three in four patients (6.7%), and six in one patient (1.7%). Fifty-three (88.3%) patients (53 aneurysms) had stable or complete occlusion, and seven (11.7%) patients had aneurysm recurrence or residual aneurysm. Among 19 patients treated with PED at follow-up, 15 aneurysms (78.9%) proceeded to complete occlusion while four (21.1%) aneurysms showed residual aneurysm. Conclusion: Endovascular embolization remains a good choice of treatment with high safety and efficacy for posterior cerebral artery aneurysms.
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spelling pubmed-85666772021-11-05 Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery Li, Xin-Yu Li, Cong-Hui Wang, Ji-Wei Liu, Jian-Feng Li, Hui Gao, Bu-Lang Front Neurol Neurology Purpose: To investigate the safety and efficacy of endovascular embolization of cerebral aneurysms at the P1–P3 segments of the posterior cerebral artery (PCA). Materials and Methods: Seventy-seven patients with 77 PCA aneurysms who were treated with endovascular embolization were enrolled, including 35 (45.5%) patients with ruptured aneurysms and 42 (54.5%) with unruptured ones. The pretreatment clinical data and aneurysm occlusion status after treatment and at follow-up were analyzed. Results: All patients were successfully treated endovascularly, including coiling alone in 10 (13.0%) patients, stent-assisted coiling in 18 (23.4%), parent artery occlusion in 25 (32.5%), and pipeline embolization device (PED) in 24 (31.2%). Complete occlusion was achieved in 48 (62.3%) aneurysms, residual neck in 4 (5.2%), and residual aneurysm in the other 25 (32.5%) at the end of embolization. Periprocedural complications occurred in eight patients, including acute thrombosis in seven (9.1%) and intraprocedural subarachnoid hemorrhage in one (1.3%), with the total complication rate of 10.4%. Follow-up was performed in 60 patients (77.9%) for 42 ± 11 months; the mRS score was 0–2 in 55 (91.7%) patients, three in four patients (6.7%), and six in one patient (1.7%). Fifty-three (88.3%) patients (53 aneurysms) had stable or complete occlusion, and seven (11.7%) patients had aneurysm recurrence or residual aneurysm. Among 19 patients treated with PED at follow-up, 15 aneurysms (78.9%) proceeded to complete occlusion while four (21.1%) aneurysms showed residual aneurysm. Conclusion: Endovascular embolization remains a good choice of treatment with high safety and efficacy for posterior cerebral artery aneurysms. Frontiers Media S.A. 2021-10-21 /pmc/articles/PMC8566677/ /pubmed/34744960 http://dx.doi.org/10.3389/fneur.2021.700516 Text en Copyright © 2021 Li, Li, Wang, Liu, Li and Gao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Li, Xin-Yu
Li, Cong-Hui
Wang, Ji-Wei
Liu, Jian-Feng
Li, Hui
Gao, Bu-Lang
Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery
title Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery
title_full Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery
title_fullStr Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery
title_full_unstemmed Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery
title_short Endovascular Management of Cerebral Aneurysms of the Posterior Cerebral Artery
title_sort endovascular management of cerebral aneurysms of the posterior cerebral artery
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566677/
https://www.ncbi.nlm.nih.gov/pubmed/34744960
http://dx.doi.org/10.3389/fneur.2021.700516
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