Downregulation of Renal Hsa-miR-127-3p Contributes to the Overactivation of Type I Interferon Signaling Pathway in the Kidney of Lupus Nephritis

MicroRNAs are involved in the pathogenesis of systemic lupus erythematosus (SLE) and dysregulated in the kidneys of lupus nephritis (LN) patients, but their pathogenic roles in LN are largely unknown. Janus Kinase 1 (JAK1) mediates the activation of the downstream signaling pathways of many inflamma...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Lingling, Han, Xiao, Jiang, Xiaoyue, Ding, Huihua, Qi, Chaojun, Yin, Zhihua, Xiao, Jianwei, Xiong, Le, Guo, Qiang, Ye, Zhizhong, Qu, Bo, Shen, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566726/
https://www.ncbi.nlm.nih.gov/pubmed/34745118
http://dx.doi.org/10.3389/fimmu.2021.747616

Ejemplares similares

Ejemplares similares