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Macrophages Are Dispensable for Postnatal Pruning of the Cochlear Ribbon Synapses

Ribbon synapses of cochlear hair cells undergo pruning and maturation before the hearing onset. In the central nervous system (CNS), synaptic pruning was mediated by microglia, the brain-resident macrophages, via activation of the complement system. Whether a similar mechanism regulates ribbon synap...

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Detalles Bibliográficos
Autores principales: Yu, Chaorong, Gao, Hui-Ming, Wan, Guoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566810/
https://www.ncbi.nlm.nih.gov/pubmed/34744631
http://dx.doi.org/10.3389/fncel.2021.736120