Effect of Bilateral Subthalamic Nucleus Deep Brain Stimulation on Pisa Syndrome in Parkinson's Disease

Objective: To observe the efficacy of bilateral subthalamic nucleus deep brain stimulation on Pisa syndrome in patients with Parkinson's disease. Methods: A total of 52 patients with Parkinson's disease who underwent deep brain stimulation in Beijing Hospital from July 1, 2016 to July 1, 2...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Jing, Cui, Zhuang, Li, Shuhua, Chen, Haibo, Su, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566818/
https://www.ncbi.nlm.nih.gov/pubmed/34744979
http://dx.doi.org/10.3389/fneur.2021.739298
_version_ 1784594097688805376
author He, Jing
Cui, Zhuang
Li, Shuhua
Chen, Haibo
Su, Wen
author_facet He, Jing
Cui, Zhuang
Li, Shuhua
Chen, Haibo
Su, Wen
author_sort He, Jing
collection PubMed
description Objective: To observe the efficacy of bilateral subthalamic nucleus deep brain stimulation on Pisa syndrome in patients with Parkinson's disease. Methods: A total of 52 patients with Parkinson's disease who underwent deep brain stimulation in Beijing Hospital from July 1, 2016 to July 1, 2020 were reviewed. The clinical data were collected for the patients who met the diagnostic criteria of Pisa syndrome on “Medication-Off” state pre-operatively. Results: Two patients met the diagnostic criteria of Pisa syndrome before operation, with a Pisa angle of 10 and 14°, respectively. The lateral trunk flexion of the two patients improved after operation. In stimulation-on/medication-off state, the Pisa angle decreased from 10 to 2° and from 14 to 6°, respectively. Conclusion: Bilateral subthalamic nucleus deep brain stimulation might have beneficial effects on lateral trunk flexion in PD patients, but the predictors of curative effect are not clear.
format Online
Article
Text
id pubmed-8566818
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-85668182021-11-05 Effect of Bilateral Subthalamic Nucleus Deep Brain Stimulation on Pisa Syndrome in Parkinson's Disease He, Jing Cui, Zhuang Li, Shuhua Chen, Haibo Su, Wen Front Neurol Neurology Objective: To observe the efficacy of bilateral subthalamic nucleus deep brain stimulation on Pisa syndrome in patients with Parkinson's disease. Methods: A total of 52 patients with Parkinson's disease who underwent deep brain stimulation in Beijing Hospital from July 1, 2016 to July 1, 2020 were reviewed. The clinical data were collected for the patients who met the diagnostic criteria of Pisa syndrome on “Medication-Off” state pre-operatively. Results: Two patients met the diagnostic criteria of Pisa syndrome before operation, with a Pisa angle of 10 and 14°, respectively. The lateral trunk flexion of the two patients improved after operation. In stimulation-on/medication-off state, the Pisa angle decreased from 10 to 2° and from 14 to 6°, respectively. Conclusion: Bilateral subthalamic nucleus deep brain stimulation might have beneficial effects on lateral trunk flexion in PD patients, but the predictors of curative effect are not clear. Frontiers Media S.A. 2021-10-21 /pmc/articles/PMC8566818/ /pubmed/34744979 http://dx.doi.org/10.3389/fneur.2021.739298 Text en Copyright © 2021 He, Cui, Li, Chen and Su. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
He, Jing
Cui, Zhuang
Li, Shuhua
Chen, Haibo
Su, Wen
Effect of Bilateral Subthalamic Nucleus Deep Brain Stimulation on Pisa Syndrome in Parkinson's Disease
title Effect of Bilateral Subthalamic Nucleus Deep Brain Stimulation on Pisa Syndrome in Parkinson's Disease
title_full Effect of Bilateral Subthalamic Nucleus Deep Brain Stimulation on Pisa Syndrome in Parkinson's Disease
title_fullStr Effect of Bilateral Subthalamic Nucleus Deep Brain Stimulation on Pisa Syndrome in Parkinson's Disease
title_full_unstemmed Effect of Bilateral Subthalamic Nucleus Deep Brain Stimulation on Pisa Syndrome in Parkinson's Disease
title_short Effect of Bilateral Subthalamic Nucleus Deep Brain Stimulation on Pisa Syndrome in Parkinson's Disease
title_sort effect of bilateral subthalamic nucleus deep brain stimulation on pisa syndrome in parkinson's disease
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566818/
https://www.ncbi.nlm.nih.gov/pubmed/34744979
http://dx.doi.org/10.3389/fneur.2021.739298
work_keys_str_mv AT hejing effectofbilateralsubthalamicnucleusdeepbrainstimulationonpisasyndromeinparkinsonsdisease
AT cuizhuang effectofbilateralsubthalamicnucleusdeepbrainstimulationonpisasyndromeinparkinsonsdisease
AT lishuhua effectofbilateralsubthalamicnucleusdeepbrainstimulationonpisasyndromeinparkinsonsdisease
AT chenhaibo effectofbilateralsubthalamicnucleusdeepbrainstimulationonpisasyndromeinparkinsonsdisease
AT suwen effectofbilateralsubthalamicnucleusdeepbrainstimulationonpisasyndromeinparkinsonsdisease

Ejemplares similares