IL-40: A New B Cell-Associated Cytokine Up-Regulated in Rheumatoid Arthritis Decreases Following the Rituximab Therapy and Correlates With Disease Activity, Autoantibodies, and NETosis

BACKGROUND: Interleukin 40 (IL-40) is a newly identified B cell-associated cytokine implicated in humoral immune responses and B cell homeostasis. As B cells play a pivotal role in autoimmunity, we investigated the function of IL-40 in rheumatoid arthritis (RA). METHODS: IL-40 expression was determi...

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Detalles Bibliográficos
Autores principales: Navrátilová, Adela, Andrés Cerezo, Lucie, Hulejová, Hana, Bečvář, Viktor, Tomčík, Michal, Komarc, Martin, Veigl, David, Tegzová, Dana, Závada, Jakub, Olejárová, Marta, Pavelka, Karel, Vencovský, Jiří, Šenolt, Ladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566875/
https://www.ncbi.nlm.nih.gov/pubmed/34745117
http://dx.doi.org/10.3389/fimmu.2021.745523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566875/
https://www.ncbi.nlm.nih.gov/pubmed/34745117
http://dx.doi.org/10.3389/fimmu.2021.745523

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