Cargando…

A Selective Neutraligand for CXCL12/SDF-1α With Beneficial Regulatory Functions in MRL/Lpr Lupus Prone Mice

Dysregulation of CXCL12/SDF-1-CXCR4/CD184 signaling is associated with inflammatory diseases and notably with systemic lupus erythematosus. Issued from the lead molecule chalcone-4, the first neutraligand of the CXCL12 chemokine, LIT-927 was recently described as a potent analogue with improved solu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schall, Nicolas, Daubeuf, François, Marsol, Claire, Gizzi, Patrick, Frossard, Nelly, Bonnet, Dominique, Galzi, Jean-Luc, Muller, Sylviane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566942/ https://www.ncbi.nlm.nih.gov/pubmed/34744730 http://dx.doi.org/10.3389/fphar.2021.752194

Ejemplares similares

An Antedrug of the CXCL12 Neutraligand Blocks Experimental Allergic Asthma without Systemic Effect in Mice
por: Daubeuf, François, et al.
Publicado: (2013)

Reduced receptor editing in lupus-prone MRL/lpr mice
por: Lamoureux, Jennifer L., et al.
Publicado: (2007)

Beneficial Effect of Bupleurum Polysaccharides on Autoimmune-Prone MRL-lpr Mice
por: Jiang, Yi-Wen, et al.
Publicado: (2012)

The new complement inhibitor CRIg/FH ameliorates lupus nephritis in lupus-prone MRL/lpr mice
por: Shi, Yu, et al.
Publicado: (2019)

Lactobacillus spp. act in synergy to attenuate splenomegaly and lymphadenopathy in lupus-prone MRL/lpr mice
por: Cabana-Puig, Xavier, et al.
Publicado: (2022)

ALW peptide ameliorates lupus nephritis in MRL/lpr mice
por: Wang, Huixia, et al.
Publicado: (2019)

The Therapeutic Effects of the Chinese Herbal Medicine, Lang Chuang Fang Granule, on Lupus-Prone MRL/lpr Mice
por: Huang, Kai-Peng, et al.
Publicado: (2016)

Anti-high Mobility Group Box 1 Antibody Ameliorates Albuminuria in MRL/lpr Lupus-Prone Mice
por: Watanabe, Haruki, et al.
Publicado: (2017)

Metformin improves renal injury of MRL/lpr lupus-prone mice via the AMPK/STAT3 pathway
por: Chen, Xiao-cui, et al.
Publicado: (2022)

hUC-MSC transplantation therapy effects on lupus-prone MRL/lpr mice at early disease stages
por: Guo, Fengbiao, et al.
Publicado: (2023)

Mesenchymal stem cells enhance CCL8 expression by podocytes in lupus-prone MRL.Fas(lpr) mice
por: Kim, Hyung Sook, et al.
Publicado: (2023)

Disease Progression in MRL/lpr Lupus-Prone Mice Is Reduced by NCS 613, a Specific Cyclic Nucleotide Phosphodiesterase Type 4 (PDE4) Inhibitor
por: Keravis, Thérèse, et al.
Publicado: (2012)

Anti-RNA polymerase I antibodies in sera of MRL lpr/lpr and MRL +/+ autoimmune mice. Correlation of antibody production with delayed onset of lupus-like disease in MRL +/+ mice
Publicado: (1985)

Formation of different abzymes in autoimmune-prone MRL-lpr/lpr mice is associated with changes in colony formation of haematopoietic progenitors
por: Andryushkova, Alexandra A, et al.
Publicado: (2007)

Effects of salvianolate on bone metabolism in glucocorticoid-treated lupus-prone B6.MRL-Fas(lpr)/J mice
por: Liu, Yanzhi, et al.
Publicado: (2016)

Murine lupus is neutrophil elastase-independent in the MRL.Fas(lpr) model
por: Gordon, Rachael A., et al.
Publicado: (2020)

T Follicular Helper Cells Mediate Expansion of Regulatory B Cells via IL-21 in Lupus-Prone MRL/lpr Mice
por: Yang, Xue, et al.
Publicado: (2013)

Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice
por: Fortner, Karen A, et al.
Publicado: (2020)

Effect of Human Mesenchymal Stem Cells on Xenogeneic T and B Cells Isolated from Lupus-Prone MRL.Fas(lpr) Mice
por: Lee, Hong Kyung, et al.
Publicado: (2020)

Self-Reactivity and the Expression of Memory Markers Vary Independently in MRL-Mp+/+ and MRL-Mp-lpr/lpr Mice
por: Smyth, Lesley, et al.
Publicado: (1992)

Nitric oxide as an inflammatory mediator in autoimmune MRL-lpr/lpr mice.
por: Weinberg, J B
Publicado: (1998)

Reduction of lupus nephritis in MRL/lpr mice by a bacterial superantigen treatment
Publicado: (1991)

The MRL/lpr Mouse Strain as a Model for Neuropsychiatric Systemic Lupus Erythematosus
por: Gulinello, Maria, et al.
Publicado: (2011)

Fecal microbiota from MRL/lpr mice exacerbates pristane-induced lupus
por: Yi, Xiaoqing, et al.
Publicado: (2023)

Influence of thymic genotype on the systemic lupus erythematosus-like disease and T cell proliferation of MRL/Mp-lpr/lpr mice
Publicado: (1981)

Galectin-9 Ameliorates Clinical Severity of MRL/lpr Lupus-Prone Mice by Inducing Plasma Cell Apoptosis Independently of Tim-3
por: Moritoki, Masahiro, et al.
Publicado: (2013)

Correction: T Follicular Helper Cells Mediate Expansion of Regulatory B Cells via IL-21 in Lupus-Prone MRL/lpr Mice
por: Yang, Xue, et al.
Publicado: (2013)

Methylprednisolone attenuates lipopolysaccharide-induced Fractalkine expression in kidney of Lupus-prone MRL/lpr mice through the NF-kappaB pathway
por: You, Yanwu, et al.
Publicado: (2015)

Correction: Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice
Publicado: (2020)

An Autophagy Modulator Peptide Prevents Lung Function Decrease and Corrects Established Inflammation in Murine Models of Airway Allergy
por: Daubeuf, François, et al.
Publicado: (2021)

Immunomodulatory effects of atorvastatin on MRL/lpr mice
por: Sun, Jing, et al.
Publicado: (2022)

Defective maintenance of T cell tolerance to a superantigen in MRL- lpr/lpr mice
Publicado: (1992)

Incorporation, distribution, and turnover of arachidonic acid within membrane phospholipids of B220+ T cells from autoimmune-prone MRL- lpr/lpr mice
Publicado: (1990)

Prolactin Increases the Frequency of Follicular T Helper Cells with Enhanced IL21 Secretion and OX40 Expression in Lupus-Prone MRL/lpr Mice
por: Alemán-García, Yolanda P., et al.
Publicado: (2021)

Transcriptomics and quantitative proteomics reveal changes after second stimulation of bone marrow-derived macrophages from lupus-prone MRL/lpr mice
por: Chen, Keyue, et al.
Publicado: (2022)

Prolactin Levels Correlate with Abnormal B Cell Maturation in MRL and MRL/lpr Mouse Models of Systemic Lupus Erythematosus-Like Disease
por: Legorreta-Haquet, Maria Victoria, et al.
Publicado: (2013)

Neuropsychiatric systemic lupus erythematosus persists despite attenuation of systemic disease in MRL/lpr mice
por: Stock, Ariel D., et al.
Publicado: (2015)

Chlorogenic Acid Relieves the Lupus Erythematosus-like Skin Lesions and Arthritis in MRL/lpr Mice
por: Wang, Ruxuan, et al.
Publicado: (2022)

Lupus pathogenesis and autoimmunity are exacerbated by high fat diet-induced obesity in MRL/lpr mice
por: Zhang, Xin, et al.
Publicado: (2023)

The contribution of L3T4+ T cells to lymphoproliferation and autoantibody production in MRL-lpr/lpr mice
Publicado: (1988)

Cannot write session to /tmp/vufind_sessions/sess_vmbujn8deq77hn140u7s219e2k