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RIPK3 and AXL Expression Study in Primary Cutaneous Melanoma Unmasks AXL as Predictor of Sentinel Node Metastasis: A Pilot Study
Malignant melanoma (MM) is the most lethal skin cancer. AXL is a tyrosine kinase receptor involved in several oncogenic processes and might play a role in blocking necroptosis (a regulated cell death mechanism) in MM through the downregulation of the necroptotic-related driver RIPK3. The aim of this...
Autores principales: | Nicolè, Lorenzo, Cappello, Filippo, Cappellesso, Rocco, Piccin, Luisa, Ventura, Laura, Guzzardo, Vincenza, Del Fiore, Paolo, Chiarion-Sileni, Vanna, Dei Tos, Angelo Paolo, Mocellin, Simone, Fassina, Ambrogio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566987/ https://www.ncbi.nlm.nih.gov/pubmed/34745951 http://dx.doi.org/10.3389/fonc.2021.728319 |
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