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RIPK3 and AXL Expression Study in Primary Cutaneous Melanoma Unmasks AXL as Predictor of Sentinel Node Metastasis: A Pilot Study

Malignant melanoma (MM) is the most lethal skin cancer. AXL is a tyrosine kinase receptor involved in several oncogenic processes and might play a role in blocking necroptosis (a regulated cell death mechanism) in MM through the downregulation of the necroptotic-related driver RIPK3. The aim of this...

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Detalles Bibliográficos
Autores principales: Nicolè, Lorenzo, Cappello, Filippo, Cappellesso, Rocco, Piccin, Luisa, Ventura, Laura, Guzzardo, Vincenza, Del Fiore, Paolo, Chiarion-Sileni, Vanna, Dei Tos, Angelo Paolo, Mocellin, Simone, Fassina, Ambrogio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566987/
https://www.ncbi.nlm.nih.gov/pubmed/34745951
http://dx.doi.org/10.3389/fonc.2021.728319

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