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Kynurenic Acid and Its Analogue SZR-72 Ameliorate the Severity of Experimental Acute Necrotizing Pancreatitis
The pathophysiology of acute pancreatitis (AP) is not well understood, and the disease does not have specific therapy. Tryptophan metabolite L-kynurenic acid (KYNA) and its synthetic analogue SZR-72 are antagonists of the N-methyl-D-aspartate receptor (NMDAR) and have immune modulatory roles in seve...
Autores principales: | Balla, Zsolt, Kormányos, Eszter Sára, Kui, Balázs, Bálint, Emese Réka, Fűr, Gabriella, Orján, Erik Márk, Iványi, Béla, Vécsei, László, Fülöp, Ferenc, Varga, Gabriella, Harazin, András, Tubak, Vilmos, Deli, Mária A., Papp, Csaba, Gácser, Attila, Madácsy, Tamara, Venglovecz, Viktória, Maléth, József, Hegyi, Péter, Kiss, Lóránd, Rakonczay, Zoltán |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567016/ https://www.ncbi.nlm.nih.gov/pubmed/34745090 http://dx.doi.org/10.3389/fimmu.2021.702764 |
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