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Large‐scale genomic sequencing reveals adaptive opportunity of targeting mutated‐PI3Kα in early and advanced HER2‐positive breast cancer

BACKGROUND: Few studies have discussed the contradictory roles of mutated‐PI3Kα in HER2‐positive (HER2+) breast cancer. Thus, we characterised the adaptive roles of PI3Kα mutations among HER2+ tumour progression. METHODS: We conducted prospective clinical sequencing of 1923 Chinese breast cancer pat...

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Detalles Bibliográficos
Autores principales:	Guo, Lin‐Wei, Li, Xiao‐Guang, Yang, Yun‐Song, Lu, Xun‐Xi, Han, Xiang‐Chen, Lang, Guan‐Tian, Chen, Li, Shao, Zhi‐Ming, Hu, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567053/ https://www.ncbi.nlm.nih.gov/pubmed/34842356 http://dx.doi.org/10.1002/ctm2.589

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