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Gasdermin E Deletion Attenuates Ureteral Obstruction- and 5/6 Nephrectomy-Induced Renal Fibrosis and Kidney Dysfunction

Renal fibrosis contributes to kidney dysfunction in various chronic kidney diseases (CKDs). Renal fibrosis can be driven by renal tubular cell death and inflammation. Deletion of gasdermin E (GSDME), an executor of pyroptosis, has been reported to suppress renal tubular cell pyroptosis in several mo...

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Detalles Bibliográficos
Autores principales:	Wu, Mengying, Xia, Weiwei, Jin, Qianqian, Zhou, Anning, Wang, Qian, Li, Shuzhen, Huang, Songming, Zhang, Aihua, Zhang, Yue, Li, Yuanyuan, Jia, Zhanjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567074/ https://www.ncbi.nlm.nih.gov/pubmed/34746148 http://dx.doi.org/10.3389/fcell.2021.754134

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