Single-cell RNA-seq of out-of-thaw mesenchymal stromal cells shows tissue-of-origin differences and inter-donor cell-cycle variations

BACKGROUND: Human Mesenchymal stromal cells (hMSCs) from various tissue sources are widely investigated in clinical trials. These MSCs are often administered to patients immediately after thawing the cryopreserved product (out-of-thaw), yet little is known about the single-cell transcriptomic landsc...

Descripción completa

Detalles Bibliográficos
Autores principales: Medrano-Trochez, Camila, Chatterjee, Paramita, Pradhan, Pallab, Stevens, Hazel Y., Ogle, Molly E., Botchwey, Edward A., Kurtzberg, Joanne, Yeago, Carolyn, Gibson, Greg, Roy, Krishnendu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567133/
https://www.ncbi.nlm.nih.gov/pubmed/34736534
http://dx.doi.org/10.1186/s13287-021-02627-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567133/
https://www.ncbi.nlm.nih.gov/pubmed/34736534
http://dx.doi.org/10.1186/s13287-021-02627-9

Ejemplares similares