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Mechanical activation of the angiotensin II type 1 receptor contributes to abdominal aortic aneurysm formation
OBJECTIVE: The angiotensin II type 1 receptor (AT1R) can be activated under conditions of mechanical stretch in some cellular systems. Whether this activity influences signaling within the abdominal aorta to promote to abdominal aortic aneurysm (AAA) development remains unknown. We evaluated the hyp...
Autores principales: | Hall, SarahRose, Ward, Nicholas D., Patel, Raj, Amin-Javaheri, Armaan, Lanford, Hayes, Grespin, R. Tyler, Couch, Christine, Xiong, Ying, Mukherjee, Rupak, Jones, Jeffrey A., Ruddy, Jean Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567200/ https://www.ncbi.nlm.nih.gov/pubmed/34761239 http://dx.doi.org/10.1016/j.jvssci.2021.07.001 |
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