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Mechanical activation of the angiotensin II type 1 receptor contributes to abdominal aortic aneurysm formation

OBJECTIVE: The angiotensin II type 1 receptor (AT1R) can be activated under conditions of mechanical stretch in some cellular systems. Whether this activity influences signaling within the abdominal aorta to promote to abdominal aortic aneurysm (AAA) development remains unknown. We evaluated the hyp...

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Detalles Bibliográficos
Autores principales: Hall, SarahRose, Ward, Nicholas D., Patel, Raj, Amin-Javaheri, Armaan, Lanford, Hayes, Grespin, R. Tyler, Couch, Christine, Xiong, Ying, Mukherjee, Rupak, Jones, Jeffrey A., Ruddy, Jean Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567200/
https://www.ncbi.nlm.nih.gov/pubmed/34761239
http://dx.doi.org/10.1016/j.jvssci.2021.07.001

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