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Metabolic turnover and dynamics of modified ribonucleosides by (13)C labeling

Tandem mass spectrometry (MS/MS) is an accurate tool to assess modified ribonucleosides and their dynamics in mammalian cells. However, MS/MS quantification of lowly abundant modifications in non-ribosomal RNAs is unreliable, and the dynamic features of various modifications are poorly understood. H...

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Detalles Bibliográficos
Autores principales: Gameiro, Paulo A., Encheva, Vesela, Dos Santos, Mariana Silva, MacRae, James I., Ule, Jernej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567201/
https://www.ncbi.nlm.nih.gov/pubmed/34634303
http://dx.doi.org/10.1016/j.jbc.2021.101294

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