Phosphoinositide-binding activity of Smad2 is essential for its function in TGF-β signaling

As a central player in the canonical TGF-β signaling pathway, Smad2 transmits the activation of TGF-β receptors at the plasma membrane (PM) to transcriptional regulation in the nucleus. Although it has been well established that binding of TGF-β to its receptors leads to the recruitment and activati...

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Detalles Bibliográficos
Autores principales: Buwaneka, Pawanthi, Ralko, Arthur, Gorai, Sukhamoy, Pham, Ha, Cho, Wonhwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567202/
https://www.ncbi.nlm.nih.gov/pubmed/34655614
http://dx.doi.org/10.1016/j.jbc.2021.101303

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