Hepsin regulates TGFβ signaling via fibronectin proteolysis

Transforming growth factor‐beta (TGFβ) is a multifunctional cytokine with a well‐established role in mammary gland development and both oncogenic and tumor‐suppressive functions. The extracellular matrix (ECM) indirectly regulates TGFβ activity by acting as a storage compartment of latent‐TGFβ, but...

Descripción completa

Detalles Bibliográficos
Autores principales: Belitškin, Denis, Pant, Shishir M, Munne, Pauliina, Suleymanova, Ilida, Belitškina, Kati, Hongisto, Hanna‐Ala, Englund, Johanna, Raatikainen, Tiina, Klezovitch, Olga, Vasioukhin, Valeri, Li, Shuo, Wu, Qingyu, Monni, Outi, Kuure, Satu, Laakkonen, Pirjo, Pouwels, Jeroen, Tervonen, Topi A, Klefström, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567232/
https://www.ncbi.nlm.nih.gov/pubmed/34515392
http://dx.doi.org/10.15252/embr.202152532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567232/
https://www.ncbi.nlm.nih.gov/pubmed/34515392
http://dx.doi.org/10.15252/embr.202152532

Ejemplares similares