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6-Thioguanine Inhibits Herpes Simplex Virus 1 Infection of Eyes

Herpes simplex virus 1 (HSV-1) infects eye corneal tissues leading to herpetic stromal keratitis (HSK), which is one of the leading causes of blindness. Here in our study, we found that 6-thioguanine (6-TG), a once clinically approved medication for child acute myelogenous leukemia, inhibited multip...

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Detalles Bibliográficos
Autores principales: Chen, Deyan, Liu, Ye, Zhang, Fang, You, Qiao, Ma, Wenyuan, Wu, Jing, Wu, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567252/
https://www.ncbi.nlm.nih.gov/pubmed/34730435
http://dx.doi.org/10.1128/Spectrum.00646-21