Cargando…

BAZ2A‐mediated repression via H3K14ac‐marked enhancers promotes prostate cancer stem cells

Prostate cancer (PCa) is one of the most prevalent cancers in men. Cancer stem cells are thought to be associated with PCa relapse. Here, we show that BAZ2A is required for PCa cells with a cancer stem‐like state. BAZ2A genomic occupancy in PCa cells coincides with H3K14ac‐enriched chromatin regions...

Descripción completa

Detalles Bibliográficos
Autores principales: Peña‐Hernández, Rodrigo, Aprigliano, Rossana, Carina Frommel, Sandra, Pietrzak, Karolina, Steiger, Seraina, Roganowicz, Marcin, Lerra, Luigi, Bizzarro, Juliana, Santoro, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567280/
https://www.ncbi.nlm.nih.gov/pubmed/34403195
http://dx.doi.org/10.15252/embr.202153014