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BAZ2A‐mediated repression via H3K14ac‐marked enhancers promotes prostate cancer stem cells
Prostate cancer (PCa) is one of the most prevalent cancers in men. Cancer stem cells are thought to be associated with PCa relapse. Here, we show that BAZ2A is required for PCa cells with a cancer stem‐like state. BAZ2A genomic occupancy in PCa cells coincides with H3K14ac‐enriched chromatin regions...
Autores principales: | Peña‐Hernández, Rodrigo, Aprigliano, Rossana, Carina Frommel, Sandra, Pietrzak, Karolina, Steiger, Seraina, Roganowicz, Marcin, Lerra, Luigi, Bizzarro, Juliana, Santoro, Raffaella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567280/ https://www.ncbi.nlm.nih.gov/pubmed/34403195 http://dx.doi.org/10.15252/embr.202153014 |
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