Defining the fetal origin of MLL-AF4 infant leukemia highlights specific fatty acid requirements

Infant MLL-AF4-driven acute lymphoblastic leukemia (ALL) is a devastating disease with dismal prognosis. A lack of understanding of the unique biology of this disease, particularly its prenatal origin, has hindered improvement of survival. We perform multiple RNA sequencing experiments on fetal, neo...

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Detalles Bibliográficos
Autores principales: Symeonidou, Vasiliki, Jakobczyk, Hélène, Bashanfer, Salem, Malouf, Camille, Fotopoulou, Foteini, Kotecha, Rishi S., Anderson, Richard A., Finch, Andrew J., Ottersbach, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567312/
https://www.ncbi.nlm.nih.gov/pubmed/34706236
http://dx.doi.org/10.1016/j.celrep.2021.109900

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