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Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation

Neutrophil extracellular traps (NETs) have been implicated in the pathogenesis of acute respiratory distress syndrome (ARDS) driven by viruses or bacteria, as well as in numerous immune-mediated disorders. Histone citrullination by the enzyme peptidylarginine deiminase 4 (PAD4) and the consequent de...

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Detalles Bibliográficos
Autores principales:	Poli, Valentina, Pui-Yan Ma, Victor, Di Gioia, Marco, Broggi, Achille, Benamar, Mehdi, Chen, Qian, Mazitschek, Ralph, Haggarty, Stephen J., Chatila, Talal A., Karp, Jeffrey M., Zanoni, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567386/ https://www.ncbi.nlm.nih.gov/pubmed/34761180 http://dx.doi.org/10.1016/j.isci.2021.103256

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