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From mRNA sensing to vaccines

The 2005 Immunity paper by Karikó et al. has been hailed as a cornerstone insight that directly led to the design and delivery of the mRNA vaccines against COVID-19. We asked experts in pathogen sensing, vaccine development, and public health to provide their perspective on the study and its implica...

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Detalles Bibliográficos
Autores principales: Fauci, Anthony S., Merad, Miriam, Swaminathan, Soumya, Hur, Sun, Topol, Eric, Fitzgerald, Kate, Reis e Sousa, Caetano, Corbett, Kizzmekia S., Bauer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567413/
https://www.ncbi.nlm.nih.gov/pubmed/34739870
http://dx.doi.org/10.1016/j.immuni.2021.10.018
Descripción
Sumario:The 2005 Immunity paper by Karikó et al. has been hailed as a cornerstone insight that directly led to the design and delivery of the mRNA vaccines against COVID-19. We asked experts in pathogen sensing, vaccine development, and public health to provide their perspective on the study and its implications.