Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer’s disease

BACKGROUND: The interaction between the brain and periphery might play a crucial role in the development of Alzheimer’s disease (AD). METHODS: Using blood transcriptomic profile data from two independent AD cohorts, we performed expression quantitative trait locus (cis-eQTL) analysis of 29 significa...

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Detalles Bibliográficos
Autores principales: Park, Young Ho, Pyun, Jung-Min, Hodges, Angela, Jang, Jae-Won, Bice, Paula J., Kim, SangYun, Saykin, Andrew J., Nho, Kwangsik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567578/
https://www.ncbi.nlm.nih.gov/pubmed/34732252
http://dx.doi.org/10.1186/s13195-021-00919-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567578/
https://www.ncbi.nlm.nih.gov/pubmed/34732252
http://dx.doi.org/10.1186/s13195-021-00919-z

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