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The design of a Bayesian adaptive clinical trial of tranexamic acid in severely injured children

BACKGROUND: Trauma is the leading cause of death and disability in children in the USA. Tranexamic acid (TXA) reduces the blood transfusion requirements in adults and children during surgery. Several studies have evaluated TXA in adults with hemorrhagic trauma, but no randomized controlled trials ha...

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Detalles Bibliográficos
Autores principales:	VanBuren, John M., Casper, T. Charles, Nishijima, Daniel K., Kuppermann, Nathan, Lewis, Roger J., Dean, J. Michael, McGlothlin, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567588/ https://www.ncbi.nlm.nih.gov/pubmed/34736498 http://dx.doi.org/10.1186/s13063-021-05737-0

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