Cargando…
A peculiar case of psychosis: anti-NMDAr encephalitis
BACKGROUND: Psychosis in pregnancy is rare and could be life-threatening. It requires prompt evaluation and proper management accordingly. Anti-N-methyl-d-aspartate receptor (anti-NMDAr) encephalitis following herpes simplex virus (HSV) infection is a rare cause of psychosis during pregnancy. CASE P...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567639/ https://www.ncbi.nlm.nih.gov/pubmed/34736411 http://dx.doi.org/10.1186/s12245-021-00389-y |
_version_ | 1784594276452139008 |
---|---|
author | Kouba, Lamia Alhosain, Dalia |
author_facet | Kouba, Lamia Alhosain, Dalia |
author_sort | Kouba, Lamia |
collection | PubMed |
description | BACKGROUND: Psychosis in pregnancy is rare and could be life-threatening. It requires prompt evaluation and proper management accordingly. Anti-N-methyl-d-aspartate receptor (anti-NMDAr) encephalitis following herpes simplex virus (HSV) infection is a rare cause of psychosis during pregnancy. CASE PRESENTATION: A 20-year-old woman at 18 weeks gestation presented with agitation and a 3-day history of hallucinations. She had a prior hospitalization for HSV encephalitis 6 weeks before. Her laboratory workup was unremarkable except for positive anti-NMDAr antibodies in the CSF. The patient was treated with high-dose corticosteroids and plasmapheresis, and she was discharged 2 weeks later fully recovered. CONCLUSIONS: Anti-NMDAr encephalitis can be the culprit behind a new-onset of psychosis in pregnancy. Early diagnosis and treatment are crucial. |
format | Online Article Text |
id | pubmed-8567639 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-85676392021-11-04 A peculiar case of psychosis: anti-NMDAr encephalitis Kouba, Lamia Alhosain, Dalia Int J Emerg Med Case Report BACKGROUND: Psychosis in pregnancy is rare and could be life-threatening. It requires prompt evaluation and proper management accordingly. Anti-N-methyl-d-aspartate receptor (anti-NMDAr) encephalitis following herpes simplex virus (HSV) infection is a rare cause of psychosis during pregnancy. CASE PRESENTATION: A 20-year-old woman at 18 weeks gestation presented with agitation and a 3-day history of hallucinations. She had a prior hospitalization for HSV encephalitis 6 weeks before. Her laboratory workup was unremarkable except for positive anti-NMDAr antibodies in the CSF. The patient was treated with high-dose corticosteroids and plasmapheresis, and she was discharged 2 weeks later fully recovered. CONCLUSIONS: Anti-NMDAr encephalitis can be the culprit behind a new-onset of psychosis in pregnancy. Early diagnosis and treatment are crucial. Springer Berlin Heidelberg 2021-11-04 /pmc/articles/PMC8567639/ /pubmed/34736411 http://dx.doi.org/10.1186/s12245-021-00389-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Kouba, Lamia Alhosain, Dalia A peculiar case of psychosis: anti-NMDAr encephalitis |
title | A peculiar case of psychosis: anti-NMDAr encephalitis |
title_full | A peculiar case of psychosis: anti-NMDAr encephalitis |
title_fullStr | A peculiar case of psychosis: anti-NMDAr encephalitis |
title_full_unstemmed | A peculiar case of psychosis: anti-NMDAr encephalitis |
title_short | A peculiar case of psychosis: anti-NMDAr encephalitis |
title_sort | peculiar case of psychosis: anti-nmdar encephalitis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567639/ https://www.ncbi.nlm.nih.gov/pubmed/34736411 http://dx.doi.org/10.1186/s12245-021-00389-y |
work_keys_str_mv | AT koubalamia apeculiarcaseofpsychosisantinmdarencephalitis AT alhosaindalia apeculiarcaseofpsychosisantinmdarencephalitis AT koubalamia peculiarcaseofpsychosisantinmdarencephalitis AT alhosaindalia peculiarcaseofpsychosisantinmdarencephalitis |