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A peculiar case of psychosis: anti-NMDAr encephalitis

BACKGROUND: Psychosis in pregnancy is rare and could be life-threatening. It requires prompt evaluation and proper management accordingly. Anti-N-methyl-d-aspartate receptor (anti-NMDAr) encephalitis following herpes simplex virus (HSV) infection is a rare cause of psychosis during pregnancy. CASE P...

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Detalles Bibliográficos
Autores principales: Kouba, Lamia, Alhosain, Dalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567639/
https://www.ncbi.nlm.nih.gov/pubmed/34736411
http://dx.doi.org/10.1186/s12245-021-00389-y
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author Kouba, Lamia
Alhosain, Dalia
author_facet Kouba, Lamia
Alhosain, Dalia
author_sort Kouba, Lamia
collection PubMed
description BACKGROUND: Psychosis in pregnancy is rare and could be life-threatening. It requires prompt evaluation and proper management accordingly. Anti-N-methyl-d-aspartate receptor (anti-NMDAr) encephalitis following herpes simplex virus (HSV) infection is a rare cause of psychosis during pregnancy. CASE PRESENTATION: A 20-year-old woman at 18 weeks gestation presented with agitation and a 3-day history of hallucinations. She had a prior hospitalization for HSV encephalitis 6 weeks before. Her laboratory workup was unremarkable except for positive anti-NMDAr antibodies in the CSF. The patient was treated with high-dose corticosteroids and plasmapheresis, and she was discharged 2 weeks later fully recovered. CONCLUSIONS: Anti-NMDAr encephalitis can be the culprit behind a new-onset of psychosis in pregnancy. Early diagnosis and treatment are crucial.
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spelling pubmed-85676392021-11-04 A peculiar case of psychosis: anti-NMDAr encephalitis Kouba, Lamia Alhosain, Dalia Int J Emerg Med Case Report BACKGROUND: Psychosis in pregnancy is rare and could be life-threatening. It requires prompt evaluation and proper management accordingly. Anti-N-methyl-d-aspartate receptor (anti-NMDAr) encephalitis following herpes simplex virus (HSV) infection is a rare cause of psychosis during pregnancy. CASE PRESENTATION: A 20-year-old woman at 18 weeks gestation presented with agitation and a 3-day history of hallucinations. She had a prior hospitalization for HSV encephalitis 6 weeks before. Her laboratory workup was unremarkable except for positive anti-NMDAr antibodies in the CSF. The patient was treated with high-dose corticosteroids and plasmapheresis, and she was discharged 2 weeks later fully recovered. CONCLUSIONS: Anti-NMDAr encephalitis can be the culprit behind a new-onset of psychosis in pregnancy. Early diagnosis and treatment are crucial. Springer Berlin Heidelberg 2021-11-04 /pmc/articles/PMC8567639/ /pubmed/34736411 http://dx.doi.org/10.1186/s12245-021-00389-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Kouba, Lamia
Alhosain, Dalia
A peculiar case of psychosis: anti-NMDAr encephalitis
title A peculiar case of psychosis: anti-NMDAr encephalitis
title_full A peculiar case of psychosis: anti-NMDAr encephalitis
title_fullStr A peculiar case of psychosis: anti-NMDAr encephalitis
title_full_unstemmed A peculiar case of psychosis: anti-NMDAr encephalitis
title_short A peculiar case of psychosis: anti-NMDAr encephalitis
title_sort peculiar case of psychosis: anti-nmdar encephalitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567639/
https://www.ncbi.nlm.nih.gov/pubmed/34736411
http://dx.doi.org/10.1186/s12245-021-00389-y
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