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Skeletal muscle methylome and transcriptome integration reveals profound sex differences related to muscle function and substrate metabolism
Nearly all human complex traits and diseases exhibit some degree of sex differences, with epigenetics being one of the main contributing factors. Various tissues display sex differences in DNA methylation; however, this has not yet been explored in skeletal muscle, despite skeletal muscle being amon...
Autores principales: | Landen, Shanie, Jacques, Macsue, Hiam, Danielle, Alvarez-Romero, Javier, Harvey, Nicholas R., Haupt, Larisa M., Griffiths, Lyn R., Ashton, Kevin J., Lamon, Séverine, Voisin, Sarah, Eynon, Nir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567658/ https://www.ncbi.nlm.nih.gov/pubmed/34732242 http://dx.doi.org/10.1186/s13148-021-01188-1 |
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