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The telomere complex and the origin of the cancer stem cell

Exquisite regulation of telomere length is essential for the preservation of the lifetime function and self-renewal of stem cells. However, multiple oncogenic pathways converge on induction of telomere attrition or telomerase overexpression and these events can by themselves trigger malignant transf...

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Detalles Bibliográficos
Autor principal: Torres-Montaner, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567692/
https://www.ncbi.nlm.nih.gov/pubmed/34736527
http://dx.doi.org/10.1186/s40364-021-00339-z