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The telomere complex and the origin of the cancer stem cell
Exquisite regulation of telomere length is essential for the preservation of the lifetime function and self-renewal of stem cells. However, multiple oncogenic pathways converge on induction of telomere attrition or telomerase overexpression and these events can by themselves trigger malignant transf...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567692/ https://www.ncbi.nlm.nih.gov/pubmed/34736527 http://dx.doi.org/10.1186/s40364-021-00339-z |