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Metronomic delivery of orally available pemetrexed-incorporated colloidal dispersions for boosting tumor-specific immunity

In this study, we developed oral pemetrexed (PMX) for metronomic dosing to enhance antitumor immunity. PMX was electrostatically complexed with positively charged lysine-linked deoxycholic acid (DL) as an intestinal permeation enhancer, forming PMX/DL, to enhance its intestinal permeability. PMX/DL...

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Detalles Bibliográficos
Autores principales:	Maharjan, Ruby, Subedi, Laxman, Pangeni, Rudra, Jha, Saurav Kumar, Kang, Seo Hee, Chang, Kwan-Young, Byun, Youngro, Choi, Jeong Uk, Park, Jin Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567874/ https://www.ncbi.nlm.nih.gov/pubmed/34730056 http://dx.doi.org/10.1080/10717544.2021.1995077

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