Cargando…

Astragalus polysacharin inhibits hepatocellular carcinoma-like phenotypes in a murine HCC model through repression of M2 polarization of tumour-associated macrophages

CONTEXT: Astragalus polysaccharin (APS), an extract of Astragalus propinquus Schischk, exerts antitumor effects in hepatocellular carcinoma (HCC). OBJECTIVE: This study investigated the mechanism of action of APS in HCC. MATERIALS AND METHODS: Tumour-associated macrophages (TAMs) were treated with A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Chun, Pan, Xin-You, Ma, Mingyun, Zhao, Jun, Zhao, Fengda, Lv, Ya-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567900/ https://www.ncbi.nlm.nih.gov/pubmed/34726570 http://dx.doi.org/10.1080/13880209.2021.1991384

Ejemplares similares

Neuroprotective Effect of Astragalus Polysacharin on Streptozotocin (STZ)-Induced Diabetic Rats
por: Zhang, Guyue, et al.
Publicado: (2019)

Astragalus Polysaccharide RAP Induces Macrophage Phenotype Polarization to M1 via the Notch Signaling Pathway
por: Wei, Wei, et al.
Publicado: (2019)

Macrophage metabolism, phenotype, function, and therapy in hepatocellular carcinoma (HCC)
por: Huang, Jingquan, et al.
Publicado: (2023)

Interference of Quercetin on Astragalus Polysaccharide-Induced Macrophage Activation
por: Li, Zhi-Peng, et al.
Publicado: (2018)

Matrix metalloproteinase‐21 promotes metastasis via increasing the recruitment and M2 polarization of macrophages in HCC
por: Zhou, Jiangfan, et al.
Publicado: (2022)

Hepatocellular carcinoma: HCC
por: Blum, Hubert E.
Publicado: (2011)

Regulation of Macrophage Activation and Polarization by HCC-Derived Exosomal lncRNA TUC339
por: Li, Xue, et al.
Publicado: (2018)

Human Hepatocellular Carcinoma (HCC)
por: Buonaguro, Luigi
Publicado: (2020)

LSD1 Facilitates Pro-Inflammatory Polarization of Macrophages by Repressing Catalase
por: Sobczak, Maciej, et al.
Publicado: (2021)

Anti-tumor effects of Astragalus on hepatocellular carcinoma in vivo
por: Li, Lian-Kun, et al.
Publicado: (2012)

Immune System and Hepatocellular Carcinoma (HCC): New Insights into HCC Progression
por: Kotsari, Maria, et al.
Publicado: (2023)

Modulatory Effects of Astragalus Polysaccharides on T-Cell Polarization in Mice with Polymicrobial Sepsis
por: Hou, Yu-Chen, et al.
Publicado: (2015)

Epigenetic Mechanisms Involved in HCV-Induced Hepatocellular Carcinoma (HCC)
por: Zhao, Pin, et al.
Publicado: (2021)

Glutamine mitigates murine burn sepsis by supporting macrophage M2 polarization through repressing the SIRT5-mediated desuccinylation of pyruvate dehydrogenase
por: Zhu, Yuanfeng, et al.
Publicado: (2022)

Astragalus polysaccharide strengthens the inflammatory and immune responses of Brucella suis S2-infected mice and macrophages
por: Shi, Qiwen, et al.
Publicado: (2019)

WTAP mediates the anti-inflammatory effect of Astragalus mongholicus polysaccharide on THP-1 macrophages
por: Long, Haijiao, et al.
Publicado: (2022)

MRI in detection of hepatocellular carcinoma (HCC)
por: Digumarthy, Subba R, et al.
Publicado: (2005)

Emerging Therapies for Hepatocellular Carcinoma (HCC)
por: Chakraborty, Eesha, et al.
Publicado: (2022)

Advances in Immunotherapy for Hepatocellular Carcinoma (HCC)
por: Bicer, Fuat, et al.
Publicado: (2023)

The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC
por: Herz, Corinna, et al.
Publicado: (2014)

lncRNA HITT Inhibits Lactate Production by Repressing PKM2 Oligomerization to Reduce Tumor Growth and Macrophage Polarization
por: Zhao, Kunming, et al.
Publicado: (2022)

Microarray and bioinformatics analyses of gene expression profiles in BALB/c murine macrophage polarization
por: Jiang, Li, et al.
Publicado: (2017)

Acetylation of MAT IIα represses tumour cell growth and is decreased in human hepatocellular cancer
por: Yang, Hong-Bin, et al.
Publicado: (2015)

Maraviroc Prevents HCC Development by Suppressing Macrophages and the Liver Progenitor Cell Response in a Murine Chronic Liver Disease Model
por: Passman, Adam M., et al.
Publicado: (2021)

Astragalus membranaceus Extract Activates Immune Response in Macrophages via Heparanase
por: Qin, Qiaojing, et al.
Publicado: (2012)

The Transcription of ZIP9 Is Associated With the Macrophage Polarization and the Pathogenesis of Hepatocellular Carcinoma
por: Gou, Yingying, et al.
Publicado: (2022)

Phlebotomus perniciosus Recombinant Salivary Proteins Polarize Murine Macrophages Toward the Anti-Inflammatory Phenotype
por: Sumova, Petra, et al.
Publicado: (2020)

Explaining the polarized macrophage pool during murine allergic lung inflammation
por: Draijer, Christina, et al.
Publicado: (2022)

Targeted xCT‐mediated Ferroptosis and Protumoral Polarization of Macrophages Is Effective against HCC and Enhances the Efficacy of the Anti‐PD‐1/L1 Response
por: Tang, Bufu, et al.
Publicado: (2022)

SHMT1 inhibits the metastasis of HCC by repressing NOX1-mediated ROS production
por: Dou, Changwei, et al.
Publicado: (2019)

Targeting the Heterogeneous Tumour-Associated Macrophages in Hepatocellular Carcinoma
por: Agirre-Lizaso, Aloña, et al.
Publicado: (2023)

Molecular Signature and Immune Landscape of HCV-Associated Hepatocellular Carcinoma (HCC): Differences and Similarities with HBV-HCC
por: De Battista, Davide, et al.
Publicado: (2021)

Resection of NAFLD/NASH-related Hepatocellular Carcinoma (HCC): Clinical Features and Outcomes Compared with HCC Due to Other Etiologies
por: Pal Chaudhary, Surendra, et al.
Publicado: (2023)

Therapeutic Effect of Astragalus Polysaccharides on Hepatocellular Carcinoma H22-Bearing Mice
por: Lai, Xiaoyu, et al.
Publicado: (2017)

NASH limits anti-tumour surveillance in immunotherapy-treated HCC
por: Pfister, Dominik, et al.
Publicado: (2021)

Serum visfatin and vaspin levels in hepatocellular carcinoma (HCC)
por: Pazgan-Simon, Monika, et al.
Publicado: (2020)

NF-Y Overexpression in Liver Hepatocellular Carcinoma (HCC)
por: Bezzecchi, Eugenia, et al.
Publicado: (2020)

A Curious Case of Vanishing Hepatocellular Carcinoma (HCC)
por: Kwei-Nsoro, Robert, et al.
Publicado: (2023)

[(18)F]-(2S,4R)4-Fluoroglutamine PET Imaging of Glutamine Metabolism in Murine Models of Hepatocellular Carcinoma (HCC)
por: Seo, Youngho, et al.
Publicado: (2022)

Asiaticoside Antagonizes Proliferation and Chemotherapeutic Drug Resistance in Hepatocellular Carcinoma (HCC) Cells
por: Ma, Ying, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2dnuudvf6pbi14obah7nd90ljn