Assembly of infectious Kaposi’s sarcoma-associated herpesvirus progeny requires formation of a pORF19 pentamer

Herpesviruses cause severe diseases particularly in immunocompromised patients. Both genome packaging and release from the capsid require a unique portal channel occupying one of the 12 capsid vertices. Here, we report the 2.6 Å crystal structure of the pentameric pORF19 of the γ-herpesvirus Kaposi’...

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Detalles Bibliográficos
Autores principales: Naniima, Peter, Naimo, Eleonora, Koch, Sandra, Curth, Ute, Alkharsah, Khaled R., Ströh, Luisa J., Binz, Anne, Beneke, Jan-Marc, Vollmer, Benjamin, Böning, Heike, Borst, Eva Maria, Desai, Prashant, Bohne, Jens, Messerle, Martin, Bauerfeind, Rudolf, Legrand, Pierre, Sodeik, Beate, Schulz, Thomas F., Krey, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568140/
https://www.ncbi.nlm.nih.gov/pubmed/34735435
http://dx.doi.org/10.1371/journal.pbio.3001423

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