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Quantitative nuclear phenotype signatures predict nodal disease in oral squamous cell carcinoma

BACKGROUND: Early-stage oral squamous cell carcinoma (OSCC) patients have a one-in-four risk of regional metastasis (LN+), which is also the most significant prognostic factor for survival. As there are no validated biomarkers for predicting LN+ in early-stage OSCC, elective neck dissection often le...

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Detalles Bibliográficos
Autores principales: Liu, Kelly Yi Ping, Zhu, Sarah Yuqi, Harrison, Alan, Chen, Zhao Yang, Guillaud, Martial, Poh, Catherine F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568158/
https://www.ncbi.nlm.nih.gov/pubmed/34735529
http://dx.doi.org/10.1371/journal.pone.0259529

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