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Bacterial profile and their antimicrobial susceptibility patterns in patients admitted at MaddaWalabu University Goba Referral Hospital, Ethiopia: a cross sectional study

BACKGROUND: Hospital acquired infections (HAIs) are one of the global concerns in resource limited settings. The aim of the study was to determine bacteria profile and their antimicrobial susceptibility patterns among patients admitted at surgical and medical wards. METHODS: A hospital based cross-s...

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Autores principales: Gemechu, Meseret Mitiku, Tadesse, Tesfaye Assefa, Takele, Getahun Negash, Bisetegn, Fithamlak Solomon, Gesese, Yonas Alem, Zelelie, Tizazu Zenebe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568252/
https://www.ncbi.nlm.nih.gov/pubmed/34795703
http://dx.doi.org/10.4314/ahs.v21i2.5
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author Gemechu, Meseret Mitiku
Tadesse, Tesfaye Assefa
Takele, Getahun Negash
Bisetegn, Fithamlak Solomon
Gesese, Yonas Alem
Zelelie, Tizazu Zenebe
author_facet Gemechu, Meseret Mitiku
Tadesse, Tesfaye Assefa
Takele, Getahun Negash
Bisetegn, Fithamlak Solomon
Gesese, Yonas Alem
Zelelie, Tizazu Zenebe
author_sort Gemechu, Meseret Mitiku
collection PubMed
description BACKGROUND: Hospital acquired infections (HAIs) are one of the global concerns in resource limited settings. The aim of the study was to determine bacteria profile and their antimicrobial susceptibility patterns among patients admitted at surgical and medical wards. METHODS: A hospital based cross-sectional study was conducted from November 2016 to July 2017 in MaddaWalabu University Goba Referral Hospital. Urine and wound swabs were processed and standard disk diffusion test was done to assess susceptibility pattern. Association among variables was determined by Chi-square test. RESULTS: Among 207 patients enrolled, 24.6% developed HAI, of which, 62.7% and 37.3% were from surgical and medical wards, respectively. The male to female ratio was 1.5:1. The age ranged from 19 to 74 years with a mean of 41.65(±16.48) years. A total 62 bacteria were isolated in which majority of the isolates were gram negative bacteria. Most isolates were resistance to most of the antibiotics tested but sensitive to Ceftriaxone, Norfloxacin and Ciprofloxacin. CONCLUSION: Due to the presence of high level drug resistant bacteria, empirical treatment to HAI may not be effective. Therefore, treatment should be based on the result of culture and sensitivity.
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spelling pubmed-85682522021-11-17 Bacterial profile and their antimicrobial susceptibility patterns in patients admitted at MaddaWalabu University Goba Referral Hospital, Ethiopia: a cross sectional study Gemechu, Meseret Mitiku Tadesse, Tesfaye Assefa Takele, Getahun Negash Bisetegn, Fithamlak Solomon Gesese, Yonas Alem Zelelie, Tizazu Zenebe Afr Health Sci Articles BACKGROUND: Hospital acquired infections (HAIs) are one of the global concerns in resource limited settings. The aim of the study was to determine bacteria profile and their antimicrobial susceptibility patterns among patients admitted at surgical and medical wards. METHODS: A hospital based cross-sectional study was conducted from November 2016 to July 2017 in MaddaWalabu University Goba Referral Hospital. Urine and wound swabs were processed and standard disk diffusion test was done to assess susceptibility pattern. Association among variables was determined by Chi-square test. RESULTS: Among 207 patients enrolled, 24.6% developed HAI, of which, 62.7% and 37.3% were from surgical and medical wards, respectively. The male to female ratio was 1.5:1. The age ranged from 19 to 74 years with a mean of 41.65(±16.48) years. A total 62 bacteria were isolated in which majority of the isolates were gram negative bacteria. Most isolates were resistance to most of the antibiotics tested but sensitive to Ceftriaxone, Norfloxacin and Ciprofloxacin. CONCLUSION: Due to the presence of high level drug resistant bacteria, empirical treatment to HAI may not be effective. Therefore, treatment should be based on the result of culture and sensitivity. Makerere Medical School 2021-06 /pmc/articles/PMC8568252/ /pubmed/34795703 http://dx.doi.org/10.4314/ahs.v21i2.5 Text en © 2021 Gemechu MM et al. https://creativecommons.org/licenses/by/4.0/Licensee African Health Sciences. This is an Open Access article distributed under the terms of the Creative commons Attribution License (https://creativecommons.org/licenses/BY/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Gemechu, Meseret Mitiku
Tadesse, Tesfaye Assefa
Takele, Getahun Negash
Bisetegn, Fithamlak Solomon
Gesese, Yonas Alem
Zelelie, Tizazu Zenebe
Bacterial profile and their antimicrobial susceptibility patterns in patients admitted at MaddaWalabu University Goba Referral Hospital, Ethiopia: a cross sectional study
title Bacterial profile and their antimicrobial susceptibility patterns in patients admitted at MaddaWalabu University Goba Referral Hospital, Ethiopia: a cross sectional study
title_full Bacterial profile and their antimicrobial susceptibility patterns in patients admitted at MaddaWalabu University Goba Referral Hospital, Ethiopia: a cross sectional study
title_fullStr Bacterial profile and their antimicrobial susceptibility patterns in patients admitted at MaddaWalabu University Goba Referral Hospital, Ethiopia: a cross sectional study
title_full_unstemmed Bacterial profile and their antimicrobial susceptibility patterns in patients admitted at MaddaWalabu University Goba Referral Hospital, Ethiopia: a cross sectional study
title_short Bacterial profile and their antimicrobial susceptibility patterns in patients admitted at MaddaWalabu University Goba Referral Hospital, Ethiopia: a cross sectional study
title_sort bacterial profile and their antimicrobial susceptibility patterns in patients admitted at maddawalabu university goba referral hospital, ethiopia: a cross sectional study
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568252/
https://www.ncbi.nlm.nih.gov/pubmed/34795703
http://dx.doi.org/10.4314/ahs.v21i2.5
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