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Emerging dynamics from high-resolution spatial numerical epidemics
Simulating nationwide realistic individual movements with a detailed geographical structure can help optimise public health policies. However, existing tools have limited resolution or can only account for a limited number of agents. We introduce Epidemap, a new framework that can capture the daily...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568339/ https://www.ncbi.nlm.nih.gov/pubmed/34652271 http://dx.doi.org/10.7554/eLife.71417 |
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author | Thomine, Olivier Alizon, Samuel Boennec, Corentin Barthelemy, Marc Sofonea, Mircea |
author_facet | Thomine, Olivier Alizon, Samuel Boennec, Corentin Barthelemy, Marc Sofonea, Mircea |
author_sort | Thomine, Olivier |
collection | PubMed |
description | Simulating nationwide realistic individual movements with a detailed geographical structure can help optimise public health policies. However, existing tools have limited resolution or can only account for a limited number of agents. We introduce Epidemap, a new framework that can capture the daily movement of more than 60 million people in a country at a building-level resolution in a realistic and computationally efficient way. By applying it to the case of an infectious disease spreading in France, we uncover hitherto neglected effects, such as the emergence of two distinct peaks in the daily number of cases or the importance of local density in the timing of arrival of the epidemic. Finally, we show that the importance of super-spreading events strongly varies over time. |
format | Online Article Text |
id | pubmed-8568339 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-85683392021-11-08 Emerging dynamics from high-resolution spatial numerical epidemics Thomine, Olivier Alizon, Samuel Boennec, Corentin Barthelemy, Marc Sofonea, Mircea eLife Computational and Systems Biology Simulating nationwide realistic individual movements with a detailed geographical structure can help optimise public health policies. However, existing tools have limited resolution or can only account for a limited number of agents. We introduce Epidemap, a new framework that can capture the daily movement of more than 60 million people in a country at a building-level resolution in a realistic and computationally efficient way. By applying it to the case of an infectious disease spreading in France, we uncover hitherto neglected effects, such as the emergence of two distinct peaks in the daily number of cases or the importance of local density in the timing of arrival of the epidemic. Finally, we show that the importance of super-spreading events strongly varies over time. eLife Sciences Publications, Ltd 2021-10-15 /pmc/articles/PMC8568339/ /pubmed/34652271 http://dx.doi.org/10.7554/eLife.71417 Text en © 2021, Thomine et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Computational and Systems Biology Thomine, Olivier Alizon, Samuel Boennec, Corentin Barthelemy, Marc Sofonea, Mircea Emerging dynamics from high-resolution spatial numerical epidemics |
title | Emerging dynamics from high-resolution spatial numerical epidemics |
title_full | Emerging dynamics from high-resolution spatial numerical epidemics |
title_fullStr | Emerging dynamics from high-resolution spatial numerical epidemics |
title_full_unstemmed | Emerging dynamics from high-resolution spatial numerical epidemics |
title_short | Emerging dynamics from high-resolution spatial numerical epidemics |
title_sort | emerging dynamics from high-resolution spatial numerical epidemics |
topic | Computational and Systems Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568339/ https://www.ncbi.nlm.nih.gov/pubmed/34652271 http://dx.doi.org/10.7554/eLife.71417 |
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