Impact of COVID-19 pandemic on liver, liver diseases, and liver transplantation programs in intensive care units

Emerging worldwide data have been suggesting that coronavirus disease 2019 (COVID-19) pandemic consequences are not limited to the respiratory and cardiovascular systems but encompass adverse gastrointestinal manifestations including acute liver injury as well. Severe cases of liver injury associate...

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Autores principales: Omar, Amr Salah, Kaddoura, Rasha, Orabi, Bassant, Hanoura, Samy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568568/
https://www.ncbi.nlm.nih.gov/pubmed/34786163
http://dx.doi.org/10.4254/wjh.v13.i10.1215
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author Omar, Amr Salah
Kaddoura, Rasha
Orabi, Bassant
Hanoura, Samy
author_facet Omar, Amr Salah
Kaddoura, Rasha
Orabi, Bassant
Hanoura, Samy
author_sort Omar, Amr Salah
collection PubMed
description Emerging worldwide data have been suggesting that coronavirus disease 2019 (COVID-19) pandemic consequences are not limited to the respiratory and cardiovascular systems but encompass adverse gastrointestinal manifestations including acute liver injury as well. Severe cases of liver injury associated with higher fatality rates were observed in critically ill patients with COVID-19. Intensive care units (ICU) have been the center of disposition of severe cases of COVID-19. This review discusses the pathogenesis of acute liver injury in ICU patients with COVID-19, and analyzes its prevalence, consequences, possible drug-induced liver injury, and the impact of the pandemic on liver diseases and transplantation programs.
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spelling pubmed-85685682021-11-15 Impact of COVID-19 pandemic on liver, liver diseases, and liver transplantation programs in intensive care units Omar, Amr Salah Kaddoura, Rasha Orabi, Bassant Hanoura, Samy World J Hepatol Review Emerging worldwide data have been suggesting that coronavirus disease 2019 (COVID-19) pandemic consequences are not limited to the respiratory and cardiovascular systems but encompass adverse gastrointestinal manifestations including acute liver injury as well. Severe cases of liver injury associated with higher fatality rates were observed in critically ill patients with COVID-19. Intensive care units (ICU) have been the center of disposition of severe cases of COVID-19. This review discusses the pathogenesis of acute liver injury in ICU patients with COVID-19, and analyzes its prevalence, consequences, possible drug-induced liver injury, and the impact of the pandemic on liver diseases and transplantation programs. Baishideng Publishing Group Inc 2021-10-27 2021-10-27 /pmc/articles/PMC8568568/ /pubmed/34786163 http://dx.doi.org/10.4254/wjh.v13.i10.1215 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Review
Omar, Amr Salah
Kaddoura, Rasha
Orabi, Bassant
Hanoura, Samy
Impact of COVID-19 pandemic on liver, liver diseases, and liver transplantation programs in intensive care units
title Impact of COVID-19 pandemic on liver, liver diseases, and liver transplantation programs in intensive care units
title_full Impact of COVID-19 pandemic on liver, liver diseases, and liver transplantation programs in intensive care units
title_fullStr Impact of COVID-19 pandemic on liver, liver diseases, and liver transplantation programs in intensive care units
title_full_unstemmed Impact of COVID-19 pandemic on liver, liver diseases, and liver transplantation programs in intensive care units
title_short Impact of COVID-19 pandemic on liver, liver diseases, and liver transplantation programs in intensive care units
title_sort impact of covid-19 pandemic on liver, liver diseases, and liver transplantation programs in intensive care units
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568568/
https://www.ncbi.nlm.nih.gov/pubmed/34786163
http://dx.doi.org/10.4254/wjh.v13.i10.1215
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