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SHP2 Potentiates the Oncogenic Activity of β-Catenin to Promote Triple-Negative Breast Cancer

Previous studies have reported dysregulated cytoplasmic and nuclear expression of the β-catenin protein in triple-negative breast cancer (TNBC) in the absence of Wnt signaling pathway dysregulation. However, the mechanism that sustains β-catenin protein dysregulation independent of Wnt signaling is...

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Detalles Bibliográficos
Autores principales:	Martin, Elisha, Agazie, Yehenew M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2021
Materias:	Signal Transduction and Functional Imaging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568672/ https://www.ncbi.nlm.nih.gov/pubmed/34389690 http://dx.doi.org/10.1158/1541-7786.MCR-21-0060

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