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AAV1.NT-3 gene therapy in a CMT2D model: phenotypic improvements in Gars(P278KY/+) mice
Glycyl–tRNA synthetase mutations are associated to the Charcot–Marie–Tooth disease type-2D. The Gars(P278KY/+) model for Charcot–Marie–Tooth disease type-2D is known best for its early onset severe neuropathic phenotype with findings including reduced axon size, slow conduction velocities and abnorm...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568849/ https://www.ncbi.nlm.nih.gov/pubmed/34755111 http://dx.doi.org/10.1093/braincomms/fcab252 |