Cargando…
Induction of Unique STAT Heterodimers by IL-21 Provokes IL-1RI Expression on CD8(+) T Cells, Resulting in Enhanced IL-1β Dependent Effector Function
IL-1β plays critical roles in the priming and effector phases of immune responses such as the differentiation, commitment, and memory formation of T cells. In this context, several reports have suggested that the IL-1β signal is crucial for CTL-mediated immune responses to viral infections and tumor...
Autores principales: | Kim, Dong Hyun, Kim, Hee Young, Lee, Won-Woo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Immunologists
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568912/ https://www.ncbi.nlm.nih.gov/pubmed/34796037 http://dx.doi.org/10.4110/in.2021.21.e33 |
Ejemplares similares
-
Endogenous IL-1 in Cognitive Function and Anxiety: A Study in IL-1RI(−/−) Mice
por: Murray, Carol L., et al.
Publicado: (2013) -
Type I IL-1 Receptor (IL-1RI) as Potential New Therapeutic Target for Bronchial Asthma
por: Lee, Jyh-Hong, et al.
Publicado: (2010) -
The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4(+) T cells
por: Dienz, Oliver, et al.
Publicado: (2009) -
SHP-1 and IL-1α conspire to provoke neutrophilic dermatoses
por: Lukens, John R, et al.
Publicado: (2014) -
Synergy of IL-21 and IL-15 in regulating CD8(+) T cell expansion and function
por: Zeng, Rong, et al.
Publicado: (2005)