Induction of Anti-Aquaporin 5 Autoantibody Production by Immunization with a Peptide Derived from the Aquaporin of Prevotella melaninogenica Leads to Reduced Salivary Flow in Mice

Sjögren's syndrome (SS) is an autoimmune disease characterized by dryness of the mouth and eyes. The glandular dysfunction in SS involves not only T cell-mediated destruction of the glands but also autoantibodies against the type 3 muscarinic acetylcholine receptor or aquaporin 5 (AQP5) that in...

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Detalles Bibliográficos
Autores principales: Lee, Ahreum, Yoo, Duck Kyun, Lee, Yonghee, Jeon, Sumin, Jung, Suhan, Noh, Jinsung, Ju, Soyeon, Hwang, Siwon, Kim, Hong Hee, Kwon, Sunghoon, Chung, Junho, Choi, Youngnim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568913/
https://www.ncbi.nlm.nih.gov/pubmed/34796038
http://dx.doi.org/10.4110/in.2021.21.e34

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