A method to estimate probability of disease and vaccine efficacy from clinical trial immunogenicity data

Vaccine efficacy is often assessed by counting disease cases in a clinical trial. A new quantitative framework proposed here (“PoDBAY,” Probability of Disease Bayesian Analysis), estimates vaccine efficacy (and confidence interval) using immune response biomarker data collected shortly after vaccina...

Descripción completa

Detalles Bibliográficos
Autores principales: Dudášová, Julie, Laube, Regina, Valiathan, Chandni, Wiener, Matthew C., Gheyas, Ferdous, Fišer, Pavel, Ivanauskaite, Justina, Liu, Frank, Sachs, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568947/
https://www.ncbi.nlm.nih.gov/pubmed/34737322
http://dx.doi.org/10.1038/s41541-021-00377-6

Ejemplares similares

Ejemplares similares