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Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants

The origin of SARS-CoV-2 variants of concern remains unclear. Here, we test whether intra-host virus evolution during persistent infections could be a contributing factor by characterizing the long-term SARS-CoV-2 infection dynamics in an immunosuppressed kidney transplant recipient. Applying RT-qPC...

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Detalles Bibliográficos
Autores principales:	Weigang, Sebastian, Fuchs, Jonas, Zimmer, Gert, Schnepf, Daniel, Kern, Lisa, Beer, Julius, Luxenburger, Hendrik, Ankerhold, Jakob, Falcone, Valeria, Kemming, Janine, Hofmann, Maike, Thimme, Robert, Neumann-Haefelin, Christoph, Ulferts, Svenja, Grosse, Robert, Hornuss, Daniel, Tanriver, Yakup, Rieg, Siegbert, Wagner, Dirk, Huzly, Daniela, Schwemmle, Martin, Panning, Marcus, Kochs, Georg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568958/ https://www.ncbi.nlm.nih.gov/pubmed/34737266 http://dx.doi.org/10.1038/s41467-021-26602-3

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